Anterior cruciate ligament (ACL) tears are a common injury, with approximately 250,000 ACL tears occurring in the United States each year. Surgical reconstruction of the ACL is considered the gold standard of treatment for active patients with ACL injury, with the goals of surgery being restoration of knee stability and prevention of further intra-articular damage. Graft options for ACL reconstruction include bone-patellar tendon-bone autograft, hamstring autograft, quadriceps autograft, and various allografts. Hamstring autografts and bone-tendon-bone autografts generally have similar outcomes in the literature. Some available evidence suggests that hamstring autografts may cause less donor-site morbidity and faster quadriceps recovery post-operatively compared with bone-tendon-bone auto-grafts. Some studies suggest that bone-tendon-bone grafts may have improved stability compared with hamstring grafts.
The purpose of this systematic review and meta-analysis was to review the published literature to compare outcomes of ACL reconstruction with hamstring autograft versus soft-tissue allograft. The hypothesis was that there would be no statistically significant differences in clinical outcomes between patients undergoing ACL reconstruction with hamstring autograft and those undergoing ACL reconstruction soft-tissue allograft.